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Article

Glutathione S-transferase genotypes in children who develop treatment-related acute myeloid malignancies.

Leukemia - 1 Feb 2000

Woo M H, Shuster J J, Chen C, Bash R O, Behm F G, Camitta B, Felix C A, Kamen B A, Pui C H, Raimondi S C, Winick N J, Amylon M D, Relling M V

Abstract excerpt

Epipodophyllotoxin-associated secondary myeloid leukemia is a devastating complication of acute lymphoblastic leukemia (ALL) therapy. The risk factors for treatment-related myeloid leukemia remain incompletely defined. Genetic deficiencies in glutathione S-transferase (GST) activities have been linked to higher frequencies of a number of human malignancies. Our objective was to determine whether the null genotype...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Leukemia, Myeloid, Acute

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Source

Identifiers

PMID: 10673738
DOI: 10.1038/sj.leu.2401660

Genes

GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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