Article
Polymorphism of the tumor necrosis factor alpha gene and waist-hip ratio in obese Korean women.
Molecules and cells - 31 Dec 2004
Um Jae-Young, Kang Byung-Ku, Lee Si-Hyeong, Shin Jo-Young, Hong Seung-Heon, Kim Hyung-Min
Abstract excerpt
A number of candidate genes have been in implicated in the pathogenesis of obesity in humans. Tumor necrosis factor-alpha (TNFalpha) is expressed primarily in adipocytes, and elevated levels of this cytokine have been linked to obesity and insulin resistance. Recently, the A allele of a polymorph...
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