Article
Tumor necrosis factor-alpha--308 G/A polymorphism in obese Caucasians.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity - 1 Apr 2001
Brand E, Schorr U, Kunz I, Kertmen E, Ringel J, Distler A, Sharma A M
Abstract excerpt
OBJECTIVE: Tumor necrosis factor-alpha (TNF-alpha) is expressed primarily in adipocytes, and elevated levels of this cytokine have been linked to obesity and insulin resistance. Recently, the A allele of a polymorphism in the 5'-flanking region of the TNF-alpha gene (G-308A) has been reported to...
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