Article
Genetic analysis of a La homolog in Drosophila melanogaster.
Nucleic acids research - 1 Mar 2000
Bai C, Tolias P P
Abstract excerpt
People afflicted with certain rheumatological auto-immune diseases produce autoantibodies directed against a select group of proteins such as the La auto-antigen. Biochemical studies have revealed La to be a promiscuous RNA-binding protein that appears to play a role in a variety of intracellular activities such as processing and/or transport of RNA polymerase III precursor transcripts and translational...
Topics
- Adenosine Triphosphatases
- Alleles
- Animals
- Autoantigens
- Drosophila melanogaster
- Gene Expression Regulation
- Genes, Insect
- Ribonucleoproteins
- Transcription Factors
- SS-B Antigen