Article
Genetic analysis of a La homolog in Drosophila melanogaster.
Nucleic acids research - 1 Mar 2000
Bai C, Tolias P P
Abstract excerpt
People afflicted with certain rheumatological auto-immune diseases produce autoantibodies directed against a select group of proteins such as the La auto-antigen. Biochemical studies have revealed La to be a promiscuous RNA-binding protein that appears to play a role in a variety of intracellular activities such as processing and/or transport of RNA polymerase III precursor transcripts and translational...
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