Article
Molecular genetic analysis of the nested Drosophila melanogaster lamin C gene.
Genetics - 1 Sept 2005
Schulze Sandra R, Curio-Penny Beatrice, Li Yuhong, Imani Reza A, Rydberg Lena, Geyer Pamela K, Wallrath Lori L
Abstract excerpt
Lamins are intermediate filaments that line the inner surface of the nuclear envelope, providing structural support and making contacts with chromatin. There are two types of lamins, A- and B-types, which differ in structure and expression. Drosophila possesses both lamin types, encoded by the LamC (A-type) and lamin Dm0 (B-type) genes. LamC is nested within an intron of the essential gene ttv. We demonstrate...
Topics
- Alleles
- Animals
- Animals, Genetically Modified
- Blotting, Western
- Drosophila Proteins
- Drosophila melanogaster
- Gene Deletion
- Gene Expression Regulation, Developmental
- Genes, Lethal
- Genes, Overlapping
- Genetic Complementation Test
- Genotype
- Hot Temperature