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Article

Most retroviral recombinations occur during minus-strand DNA synthesis.

Journal of virology - 1 Mar 2000

Zhang J, Tang L Y, Li T, Ma Y, Sapp C M

Abstract excerpt

Retroviral RNA molecules are plus, or sense in polarity, equivalent to mRNA. During reverse transcription, the first strand of the DNA molecule synthesized is minus-strand DNA. After the minus strand is polymerized, the plus-strand DNA is synthesized using the minus-strand DNA as the template. In this study, a helper cell line that contains two proviruses with two different mutated gfp genes was constructed....

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Share to DNA, Viral
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Transformation, Genetic

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Source

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Identifiers

PMID: 10666262
DOI: 10.1128/jvi.74.5.2313-2322.2000
PMCID: PMC111713

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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