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Article

A transcriptionally active subgenomic promoter supports homologous crossovers in a plus-strand RNA virus.

Journal of virology - 1 Jun 2003

Wierzchoslawski Rafal, Dzianott Aleksandra, Kunimalayan Selvi, Bujarski Jozef J

Abstract excerpt

Genetic RNA recombination plays an important role in viral evolution, but its molecular mechanism is not well understood. In this work we describe homologous RNA recombination activity that is supported by a subgenomic promoter (sgp) region in the RNA3 segment of brome mosaic bromovirus (BMV), a tripartite plus-strand RNA virus. The crossover frequencies were determined by coinoculations with pairs of BMV RNA3...

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Identifiers

PMID: 12767997
DOI: 10.1128/jvi.77.12.6769-6776.2003
PMCID: PMC156210

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Source receipt: pubmed, retrieved 7 Sept 2026.

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