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Article

Genetic recombination of poliovirus in a cell-free system.

Proceedings of the National Academy of Sciences of the United States of America - 9 Dec 1997

Duggal R, Cuconati A, Gromeier M, Wimmer E

Abstract excerpt

Genetic recombination of plus-strand RNA viruses is an important process for promoting genetic variation. By using genetically marked poliovirus RNAs, we have demonstrated that genetic recombination can occur in a cell-free system that generates infective virus from added poliovirus RNA. Recombinant polioviruses were isolated, and the region of crossing over was roughly mapped. Recombinants could be isolated even...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 9391105
DOI: 10.1073/pnas.94.25.13786
PMCID: PMC28385

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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