Article
[Molecular and genetic features of gastrointestinal stromal tumors (GIST)].
Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru - 1 Jan 2000
Buleje S José, Yábar B Alejandro, Guevara-Fujita María, Fujita Ricardo
Abstract excerpt
Gastrointestinal stromal tumors (GISTs) are mesenchymal neoplasms typically arising in the stomach, small intestine, colon, and other sites in the abdominal cavity and its identification has improved dramatically mainly due to better criteria in its detection. Most GISTs tumors harbor activating mutations in the tyrosine kinase receptor c-KIT or platelet derived growth factor receptor-alpha (PDGFRA). Those...
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