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Article

Microsatellites proximal to leptin and leptin receptor as risk factors for spina bifida.

Teratology - 1 Mar 2000

Shaw G M, Barber R, Todoroff K, Lammer E J, Finnell R H

Abstract excerpt

Several recent studies have observed an association between neural tube defect risk and prepregnant obesity. This association was generally stronger for spina bifida and was observed irrespective of additional maternal factors, including periconceptional intake of vitamin supplements. Other studies have identified mutations within the genes that code for leptin (LEP) and its receptor (LEPR), which have been...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10661913
DOI: 10.1002/(SICI)1096-9926(200003)61:3<231::AID-TERA11>3.0.CO;2-L

Genes

LEP
LEPR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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