Article
Leptin and Leptin Receptor Polymorphisms in Infants and Their Parents: Correlation with Preterm Birth.
Genes - 22 Jan 2024
Savino Francesco, Sardo Allegra, Gambarino Stefano, Dini Maddalena, Clemente Anna, Pau Anna, Galliano Ilaria, Bergallo Massimiliano
Abstract excerpt
It has been proven that single-nucleotide polymorphisms (SNPs) in LEP and LEPR genes could predispose individuals to an increased risk of pregnancy adverse outcomes (PAOs) such as recurrent pregnancy loss (RPL) and pre-eclampsia. Preterm birth (PTB) is the leading cause of infant mortality. We decided to investigate the correlation between PTB and LEP and LEPR SNPs. The study cohort included families who...
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