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Molecular Cloning and Characterization of Multispecific Organic Anion Transporter 4 Expressed in the Placenta

1 Feb 2000

Abstract excerpt

A cDNA encoding a novel multispecific organic anion transporter, OAT4, was isolated from a human kidney cDNA library. The OAT4 cDNA consisted of 2210 base pairs that encoded a 550-amino acid residue protein with 12 putative membrane-spanning domains. The amino acid sequence of OAT4 showed 38 to 44% identity to those of other members of the OAT family. Northern blot analysis revealed that OAT4 mRNA is abundantly...

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PMID: 10660625
DOI: 10.1074/jbc.275.6.4507

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