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Article

A yeast heterogeneous nuclear ribonucleoprotein complex associated with RNA polymerase II.

Genetics - 1 Feb 2000

Conrad N K, Wilson S M, Steinmetz E J, Patturajan M, Brow D A, Swanson M S, Corden J L

Abstract excerpt

Recent evidence suggests a role for the carboxyl-terminal domain (CTD) of the largest subunit of RNA polymerase II (pol II) in pre-mRNA processing. The yeast NRD1 gene encodes an essential RNA-binding protein that shares homology with mammalian CTD-binding proteins and is thought to regulate mRNA abundance by binding to a specific cis-acting element. The present work demonstrates genetic and physical interactions...

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Identifiers

PMID: 10655211
DOI: 10.1093/genetics/154.2.557
PMCID: PMC1460961

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