Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inhibition of NOS enhances pulmonary vascular changes in stroke-prone spontaneously hypertensive rats.

American journal of physiology. Lung cellular and molecular physiology - 1 Jan 2000

Mathew R, Fan N Y, Yuan N, Chander P N, Gewitz M H, Stier C T

Abstract excerpt

To determine the effects of chronic nitric oxide (NO) blockade on the pulmonary vasculature, 58-day-old spontaneously hypertensive rats of the stroke-prone substrain (SHRSP) and Wistar-Kyoto rats (WKY) received N(omega)-nitro-L-arginine (L-NNA; 15 mg. kg(-1). day(-1) orally for 8 days). Relaxation to acetylcholine (ACh) in hilar pulmonary arteries (PAs), the ratio of right ventricular (RV) to body weight (RV/BW)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Vessels
Share to Cyclic GMP

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hypertension, Pulmonary

Share to Hypertrophy, Left Ventricular

Share to Nitric Oxide Synthase

Share to Rats, Inbred SHR

Share to Rats, Inbred WKY

Share to Vasodilation

Source

Identifiers

PMID: 10645894
DOI: 10.1152/ajplung.2000.278.1.L81

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inhibition of NOS enhances pulmonary vascular changes in stroke-prone spontaneously hypertensive rats.PMID 10645894Read ↗

Endothelium-dependent relaxation in pulmonary arteries of L-NAME-treated Wistar and stroke-prone spontaneously hypertensive rats.Semantic proximity Read ↗

Reduced hypoxic pulmonary vascular remodeling by nitric oxide from the endothelium.Semantic proximity Read ↗

Atorvastatin causes depressor and sympatho-inhibitory effects with upregulation of nitric oxide synthases in stroke-prone spontaneously hypertensive rats.Semantic proximity Read ↗

Sodium, survival, and the mechanical properties of the carotid artery in stroke-prone hypertensive rats.Semantic proximity Read ↗

Impaired Pulmonary Arterial Vasoconstriction and Nitric Oxide-Mediated Relaxation Underlie Severe Pulmonary Hypertension in the Sugen-Hypoxia Rat Model.Semantic proximity Read ↗

Effect of a selective endothelin receptor A blocker on cardiovascular remodeling in uninephrectomized spontaneously hypertensive rats of the stroke-prone strain.Semantic proximity Read ↗

Myogenic and structural properties of cerebral arteries from the stroke-prone spontaneously hypertensive rat.Semantic proximity Read ↗

Reduction of the soluble cyclic GMP vasorelaxing system in the vascular wall of stroke-prone spontaneously hypertensive rats: effect of the alpha1 -receptor blocker doxazosin.Semantic proximity Read ↗

Suppressive action of docosahexaenoic acid enriched-Euglena on reduction of endothelium-dependent relaxation in stroke-prone spontaneously hypertensive rats (SHRSP).Semantic proximity Read ↗

Role of nNOS in blood pressure regulation in eNOS null mutant mice.Semantic proximity Read ↗

Inhibition of Rac1-derived reactive oxygen species in nucleus tractus solitarius decreases blood pressure and heart rate in stroke-prone spontaneously hypertensive rats.Semantic proximity Read ↗

Predisposition of spontaneously hypertensive rats to develop renal injury during nitric oxide synthase inhibition.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.