Article
Inhibition of Rac1-derived reactive oxygen species in nucleus tractus solitarius decreases blood pressure and heart rate in stroke-prone spontaneously hypertensive rats.
Hypertension (Dallas, Tex. : 1979) - 1 Jul 2007
Nozoe Masatsugu, Hirooka Yoshitaka, Koga Yasuaki, Sagara Yoji, Kishi Takuya, Engelhardt John F, Sunagawa Kenji
Abstract excerpt
Reactive oxygen species (ROS) in the brain are thought to contribute to the neuropathogenesis of hypertension by enhancing sympathetic nervous system activity. The nucleus tractus solitarius (NTS), which receives afferent input from baroreceptors, has an important role in cardiovascular regulatio...
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