Article
Angiotensin converting enzyme gene I/D polymorphism in essential hypertension and nephroangiosclerosis.
Kidney international - 1 Jun 1998
Fernández-Llama P, Poch E, Oriola J, Botey A, Coll E, Darnell A, Rivera F, Revert L
Abstract excerpt
An insertion/deletion (I/D) polymorphism of the angiotensin converting enzyme (ACE) gene significantly influences circulating ACE levels and plays a role in the development of target organ damage, that is, left ventricular hypertrophy in essential hypertension (EH), and microalbuminuria in diabet...
Topics
- Adult
- Albuminuria
- Alleles
- DNA Transposable Elements
- Female
- Gene Deletion
- Gene Frequency
- Genotype
- Hemodynamics
- Humans
- Hypertension
- Male
- Middle Aged
- Nephrosclerosis
- Peptidyl-Dipeptidase A
- Polymorphism, Genetic
- Renal Circulation
- Retrospective Studies