Article
Angiotensin converting enzyme gene I/D polymorphism in essential hypertension and nephroangiosclerosis.
Kidney international - 1 Jun 1998
Fernández-Llama P, Poch E, Oriola J, Botey A, Coll E, Darnell A, Rivera F, Revert L
Abstract excerpt
An insertion/deletion (I/D) polymorphism of the angiotensin converting enzyme (ACE) gene significantly influences circulating ACE levels and plays a role in the development of target organ damage, that is, left ventricular hypertrophy in essential hypertension (EH), and microalbuminuria in diabetes mellitus. We have examined the role of the I/D polymorphism in essential hypertensive patients with renal...
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