Article
Association of angiotensin converting enzyme (insertion/deletion) gene polymorphism with essential hypertension in northern Indian subjects.
Genetic testing and molecular biomarkers - 1 Mar 2012
Srivastava Kamna, Sundriyal Ruchi, Meena Prakash C, Bhatia Jagriti, Narang Rajiv, Saluja Daman
Abstract excerpt
OBJECTIVE: Essential hypertension is a multifactorial disease in which genetic and environmental factors play an important role. The renin-angiotensin system (RAS) is known to play a critical role in the homeostasis of blood pressure. Angiotensin-I converting enzyme (ACE) is a significant component of RAS, and an insertion/deletion (I/D) polymorphism in its gene has been implicated in predisposition to...
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