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Article

Lack of cyclooxygenase-2 inhibits growth of teratocarcinomas in mice.

Experimental cell research - 1 Feb 2000

Zhang X, Morham S G, Langenbach R, Baggs R B, Young D A

Abstract excerpt

Two isoforms of cyclooxygenase (COX-1 or COX-2) have been identified in the prostanoid biosynthetic pathway. The constitutive form, COX-1, is thought to maintain cellular homeostasis and the inducible form, COX-2, is recognized as a primary response gene thought to be involved in modulating cell proliferation and differentiation. To further characterize the role of the cyclooxygenases in cell proliferation,...

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Source

Identifiers

PMID: 10640421
DOI: 10.1006/excr.1999.4758

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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