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Article

Mutation analysis of pertussis toxin promoter.

Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi - 1 Sept 1999

Wo Y Y, Chiu S C, Lu C H

Abstract excerpt

The improving of the expression efficiency of a pertussis toxin (PT) promoter was believed to be a critical issue for the production of PT in acellular vaccine development. In this study, we have isolated a PT promoter region from the genome of a pertussis strain ATCC 9340. Based on the promoter sequence, a series of mutant PT promoters have been generated and subjected to in vitro gel shift analysis and in vivo...

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PMID: 10637714

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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