Article
The private hepatocyte nuclear factor-1alpha G319S variant is associated with plasma lipoprotein variation in Canadian Oji-Cree.
Arteriosclerosis, thrombosis, and vascular biology - 1 Jan 2000
Hegele R A, Cao H, Harris S B, Hanley A J, Zinman B, Connelly P W
Abstract excerpt
We previously showed an extremely strong association between type 2 diabetes and a private polymorphism, namely G319S, in the hepatocyte nuclear transcription factor (HNF)-1alpha. Because HNF-1alpha is involved in the transcription of several apolipoprotein genes, we tested for an association between the private HNF1A G319S variant and plasma lipoproteins in a sample of 55 unrelated Oji-Cree subjects with type 2...
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