Article
Gender, obesity, hepatic nuclear factor-1alpha G319S and the age-of-onset of type 2 diabetes in Canadian Oji-Cree.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity - 1 Aug 2000
Hegele R A, Cao H, Harris S B, Zinman B, Hanley A J, Anderson C M
Abstract excerpt
Among the Oji-Cree of northern Ontario, women have both a higher prevalence and an earlier onset of type 2 diabetes compared to men. We studied the relationship between HNF1A S319 and both the presence of and the age-of-onset of type 2 diabetes in women and men separately. We found that: 1) in women, there was a significant difference in the mean age-of-onset of type 2 diabetes according to HNF1A genotype; and 2)...
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