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Genes, environment and Oji-Cree type 2 diabetes.

Clinical biochemistry - 1 May 2003

Hegele Robert A, Zinman Bernard, Hanley Anthony J G, Harris Stewart B, Barrett P Hugh, Cao Henian

Abstract excerpt

The prevalence of type 2 diabetes in Canadian Oji-Cree is among the highest in the world. Our research has uncovered genetic determinants of Oji-Cree type 2 diabetes and related metabolic traits. The most important genetic discovery by far was the private G319S mutation in transcription factor HNF-1alpha, encoded by the HNF1A gene. HNF1A G319S was discovered by candidate gene sequencing and would have been missed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12726923
DOI: 10.1016/s0009-9120(03)00004-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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