Article
Association testing of variants in the hepatocyte nuclear factor 4alpha gene with risk of type 2 diabetes in 7,883 people.
Diabetes - 1 Mar 2005
Winckler Wendy, Graham Robert R, de Bakker Paul I W, Sun Maria, Almgren Peter, Tuomi Tiinamaija, Gaudet Daniel, Hudson Thomas J, Ardlie Kristin G, Daly Mark J, Hirschhorn Joel N, Groop Leif, Altshuler David
Abstract excerpt
Two recent publications reported association of common polymorphisms in the P2 promoter of hepatocyte nuclear factor 4alpha (HNF4alpha) (the MODY1 gene) with risk for type 2 diabetes. We attempted to reproduce this putative association by genotyping 11 single nucleotide polymorphism (SNPs) spanni...
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