Article
BRCA1 mutation testing for Japanese patients with ovarian cancer in breast cancer screening.
Breast cancer research and treatment - 1 Nov 1999
Yamashita Y, Sagawa T, Fujimoto T, Sugawara T, Yamada H, Hoshi N, Sakuragi N, Ishioka C, Fujimoto S
Abstract excerpt
From February 1996 to April 1998, 2967 women received screening for breast cancer in the gynecologic ambulatory practice of the Hokkaido University Hospital. In 116 Japanese women with epithelial ovarian cancer, mutation analysis of BRCA1 exon 11 in genomic DNA was performed by the stop codon (SC) assay and DNA sequence analysis. Clinicopathological factors were also investigated in these patients. The aim of...
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