Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutations in the BRCA1 gene in Japanese breast cancer patients.

Human mutation - 1 Jan 1996

Katagiri T, Emi M, Ito I, Kobayashi K, Yoshimoto M, Iwase T, Kasumi F, Miki Y, Skolnick M H, Nakamura Y

Abstract excerpt

Predisposing germline mutations in the BRCA1 gene were identified recently in families with 17 q-linked breast and ovarian cancers. Using single-strand conformation polymorphism (SSCP) analysis, we examined primary breast cancers for mutations in coding exons of BRCA1 in a panel of 103 patients,...

Topics

Join the communities discussing this publication.

Base Sequence
DNA, Neoplasm
DNA Primers
Japan
Molecular Sequence Data
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single-Stranded Conformational

Transcription Factors

Source

Identifiers

PMID: 8723683
DOI: 10.1002/(SICI)1098-1004(1996)7:4<334::AID-HUMU7>3.0.CO;2-8

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-8723683-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutations in the BRCA1 gene in Japanese breast cancer patients.PMID 8723683Read ↗

Mutation analysis of the BRCA1 gene in 76 Japanese ovarian cancer patients: four germline mutations, but no evidence of somatic mutation.Semantic proximity Read ↗

Multiplex mutation screening of the BRCA1 gene in 1000 Japanese breast cancers.Semantic proximity Read ↗

High proportion of missense mutations of the BRCA1 and BRCA2 genes in Japanese breast cancer families.Semantic proximity Read ↗

BRCA1 germline mutations and tumor characteristics in Chinese women with familial or early-onset breast cancer.Semantic proximity Read ↗

BRCA1 and BRCA2 mutation status and cancer family history of Danish women affected with multifocal or bilateral breast cancer at a young age.Semantic proximity Read ↗

Study of BRCA1 gene in hereditary breast and ovarian cancer.Semantic proximity Read ↗

BRCA1-positive breast cancers in young women from Poland.Semantic proximity Read ↗

[Relationship between mutation of BRCA1 and susceptibility to early onset of breast cancer].Semantic proximity Read ↗

BRCA1 mutations in African Americans.Semantic proximity Read ↗

The analysis of BRCA1 mutations in eastern Chinese patients with early onset breast cancer and affected relatives.Semantic proximity Read ↗

[Analysis of BRCA1 mutations in Chinese patients with early onset breast cancer and affected relatives].Semantic proximity Read ↗

A novel de novo BRCA1 mutation in a Chinese woman with early onset breast cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.