Article
Polymorphisms of Dopamine Receptor Genes and Risk of L-Dopa-Induced Dyskinesia in Parkinson's Disease.
International journal of molecular sciences - 24 Jan 2017
Comi Cristoforo, Ferrari Marco, Marino Franca, Magistrelli Luca, Cantello Roberto, Riboldazzi Giulio, Bianchi Maria Laura Ester, Bono Giorgio, Cosentino Marco
Abstract excerpt
L-dopa-induced dyskinesia (LID) is a frequent motor complication of Parkinson's disease (PD), associated with a negative prognosis. Previous studies showed an association between dopamine receptor (DR) gene (DR) variants and LID, the results of which have not been confirmed. The present study is aimed to determine whether genetic differences of DR are associated with LID in a small but well-characterized cohort...
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