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Article

Temperature inducible beta-sheet structure in the transactivation domains of retroviral regulatory proteins of the Rev family.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy - 1 Nov 1999

Thumb W, Graf C, Parslow T, Schneider R, Auer M

Abstract excerpt

The interaction of the human immunodeficiency virus type 1 (HIV-1) regulatory protein Rev with cellular cofactors is crucial for the viral life cycle. The HIV-1 Rev transactivation domain is functionally interchangeable with analog regions of Rev proteins of other retroviruses suggesting common folding patterns. In order to obtain experimental evidence for similar structural features mediating protein-protein...

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Identifiers

PMID: 10629982
DOI: 10.1016/s1386-1425(99)00162-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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