Mechanism of osmotic activation of the quaternary ammonium compound transporter (QacT) of Lactobacillus plantarum.

doi:10.1128/JB.180.21.5540-5546.1998

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Article

Mechanism of osmotic activation of the quaternary ammonium compound transporter (QacT) of Lactobacillus plantarum.

Journal of bacteriology - 1 Nov 1998

Glaasker E, Heuberger E H, Konings W N, Poolman B

Abstract excerpt

The accumulation of quaternary ammonium compounds in Lactobacillus plantarum is mediated via a single transport system with a high affinity for glycine betaine (apparent Km of 18 microM) and carnitine and a low affinity for proline (apparent Km of 950 microM) and other analogues. Mutants defectiv...

Topics

Betaine
Carrier Proteins
Drug Resistance, Microbial
Kinetics
Lactobacillus
Mutation
Osmotic Pressure
Proline
Quaternary Ammonium Compounds

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