Article
Mechanism of osmotic activation of the quaternary ammonium compound transporter (QacT) of Lactobacillus plantarum.
Journal of bacteriology - 1 Nov 1998
Glaasker E, Heuberger E H, Konings W N, Poolman B
Abstract excerpt
The accumulation of quaternary ammonium compounds in Lactobacillus plantarum is mediated via a single transport system with a high affinity for glycine betaine (apparent Km of 18 microM) and carnitine and a low affinity for proline (apparent Km of 950 microM) and other analogues. Mutants defective in the uptake of glycine betaine were generated by UV irradiation and selected on the basis of resistance to...
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