Article
Thermoprotection by glycine betaine and choline.
Microbiology (Reading, England) - 1 Sept 1999
Caldas Teresa, Demont-Caulet Nathalie, Ghazi Alexandre, Richarme Gilbert
Abstract excerpt
Glycine betaine is mostly known as an osmoprotectant. It is involved in the osmotic adaptation of eukaryotic and bacterial cells, and accumulates up to 1 M inside cells subjected to an osmotic upshock. Since, like other osmolytes, it can act as a protein stabilizer, its thermoprotectant properties were investigated. In vitro, like protein chaperones such as DnaK, glycine betaine and choline protect citrate...
Topics
- Betaine
- Choline
- Citrate (si)-Synthase
- Escherichia coli
- Escherichia coli Proteins
- HSP70 Heat-Shock Proteins
- Heat-Shock Response
- Mutation
- Protein Folding
- beta-Galactosidase
