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Article

Identification of the zinc ligands in cobalamin-independent methionine synthase (MetE) from Escherichia coli.

Biochemistry - 30 Nov 1999

Zhou Z S, Peariso K, Penner-Hahn J E, Matthews R G

Abstract excerpt

Cobalamin-independent methionine synthase (MetE) from Escherichia coli catalyzes the transfer of a methyl group from methyltetrahydrofolate to homocysteine to form tetrahydrofolate and methionine. It contains 1 equiv of zinc that is essential for its catalytic activity. Extended X-ray absorption fine structure analysis of the zinc-binding site has suggested tetrahedral coordination with two sulfur (cysteine) and...

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PMID: 10625458
DOI: 10.1021/bi992062b

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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