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Article

On the relevance of the Met-turn methionine in metzincins.

The Journal of biological chemistry - 30 Apr 2010

Tallant Cynthia, García-Castellanos Raquel, Baumann Ulrich, Gomis-Rüth F Xavier

Abstract excerpt

The metzincins are a clan of metallopeptidases consisting of families that share a series of structural elements. Among them is the Met-turn, a tight 1,4-turn found directly below the zinc-binding site, which is structurally and spatially conserved and invariantly shows a methionine at position 3 in all metzincins identified. The reason for this conservation has been a matter of debate since its discovery. We...

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Identifiers

PMID: 20202937
DOI: 10.1074/jbc.M109.083378
PMCID: PMC2859557

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