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Article

The conserved methionine residue of the metzincins: a site-directed mutagenesis study.

Journal of molecular biology - 23 Nov 2001

Hege T, Baumann U

Abstract excerpt

The metalloprotease clan of the metzincins derive their name from the presence of a conserved methionine residue that is located on the C-terminal side of the zinc-binding consensus sequence HEXXHXXGXXH. This methionine residue is located in a rather divergent part of the primary sequence but is structurally very well conserved. It is located under the pyramidal base of the three histidine residues that...

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Identifiers

PMID: 11718552
DOI: 10.1006/jmbi.2001.5125

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