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Article

Imprinting, the X-chromosome, and the male brain: explaining sex differences in the liability to autism.

Pediatric research - 1 Jan 2000

Skuse D H

Abstract excerpt

Males are at least four times more likely to develop autism than females. Among relatives with a broader autistic phenotype, males predominate too. Autism is a highly heritable disorder, yet genome scans have not revealed any predisposing loci on the sex chromosomes. A nongenetic explanation for male vulnerability, such as exposure to prenatal androgens, is unlikely for a variety of reasons. A novel genetic...

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PMID: 10625077
DOI: 10.1203/00006450-200001000-00006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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