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Article

Why are autism spectrum conditions more prevalent in males?

PLoS biology - 1 Jun 2011

Baron-Cohen Simon, Lombardo Michael V, Auyeung Bonnie, Ashwin Emma, Chakrabarti Bhismadev, Knickmeyer Rebecca

Abstract excerpt

Autism Spectrum Conditions (ASC) are much more common in males, a bias that may offer clues to the etiology of this condition. Although the cause of this bias remains a mystery, we argue that it occurs because ASC is an extreme manifestation of the male brain. The extreme male brain (EMB) theory, first proposed in 1997, is an extension of the Empathizing-Systemizing (E-S) theory of typical sex differences that...

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Identifiers

PMID: 21695109
DOI: 10.1371/journal.pbio.1001081
PMCID: PMC3114757

Genes

EMB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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