Article
The imprinted brain: how genes set the balance between autism and psychosis.
Epigenomics - 1 Jun 2011
Badcock Christopher
Abstract excerpt
The imprinted brain theory proposes that autism spectrum disorder (ASD) represents a paternal bias in the expression of imprinted genes. This is reflected in a preference for mechanistic cognition and in the corresponding mentalistic deficits symptomatic of ASD. Psychotic spectrum disorder (PSD) would correspondingly result from an imbalance in favor of maternal and/or X-chromosome gene expression. If differences...
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