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Article

Multiple ramp domains are required for generation of amylin receptor phenotype from the calcitonin receptor gene product.

Biochemical and biophysical research communications - 7 Jan 2000

Zumpe E T, Tilakaratne N, Fraser N J, Christopoulos G, Foord S M, Sexton P M

Abstract excerpt

Calcitonin (CT), calcitonin gene-related peptide (CGRP), amylin, and adrenomedullin constitute a family of structurally related peptides that signal via either the calcitonin receptor-like receptor or the CT receptor, with receptor phenotype determined by coexpression of one of the three receptor activity-modifying proteins (RAMPs). The nature of the interaction between the receptor and RAMP was investigated...

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Source

Identifiers

PMID: 10623626
DOI: 10.1006/bbrc.1999.1943

Genes

RAMP1
RAMP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Multiple ramp domains are required for generation of amylin receptor phenotype from the calcitonin receptor gene product.PMID 10623626Read ↗

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