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Article

A critical role for the short intracellular C terminus in receptor activity-modifying protein function.

Molecular pharmacology - 1 Nov 2006

Udawela Madhara, Christopoulos George, Morfis Maria, Christopoulos Arthur, Ye Siying, Tilakaratne Nanda, Sexton Patrick M

Abstract excerpt

Receptor activity-modifying proteins (RAMPs) interact with and modify the behavior of the calcitonin receptor (CTR) and calcitonin receptor-like receptor (CLR). We have examined the contribution of the short intracellular C terminus, using constructs that delete the last eight amino acids of each RAMP. C-Terminal deletion of individual RAMPs had little effect on the signaling profile induced when complexed with...

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Share to Cyclic AMP
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GTP-Binding Protein alpha Subunits, Gs

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Source

Identifiers

PMID: 16912219
DOI: 10.1124/mol.106.024257

Genes

RAMP1
RAMP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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