Article
CTLA4 gene polymorphism contributes to the mode of onset of diabetes with antiglutamic acid decarboxylase antibody in Japanese patients: genetic analysis of diabetic patients with antiglutamic acid decarboxylase antibody.
Diabetic medicine : a journal of the British Diabetic Association - 1 Sept 2001
Abe T, Yamaguchi Y, Takino H, Fujita N, Yamauchi-Degawa M, Ozaki M, Yamakawa K, Sera Y, Sakamaki H, Uotani S, Kawasaki E, Awata T, Yamasaki H, Eguchi K
Abstract excerpt
AIM: The mode of onset is occasionally similar in Type 1 and Type 2 diabetes mellitus, and some patients with Type 2 diabetes are positive for antiglutamic acid decarboxylase antibody (GAD Ab). We investigated the contribution of Type 1 diabetes susceptibility genes to the progression of the insulin-deficient state and mode of onset of Type 2 diabetes in GAD Ab-positive (GAD-Ab+) patients. We examined the...
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