Article
Angiotensin II type 1 receptor gene polymorphism and mitral valve prolapse syndrome.
American heart journal - 1 Jan 2000
Szombathy T, Jánoskúti L, Szalai C, Császár A, Miklósi M, Mészáros Z, Kempler P, László Z, Fenyvesi T, Romics L
Abstract excerpt
BACKGROUND: Mitral valve prolapse syndrome (MVPS), a term applied to patients who have a variety of symptoms, has been associated with autonomic or neuroendocrine dysfunction. Recent evidence suggests that effects of angiotensin II mediated by the angiotensin II type 1 (AT(1)) receptor are involved in modulation of cardiovascular autonomic control in human beings. Association of a genetic polymorphism (A-C(1166))...
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