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Article

AGT and ACE genes influence classic mitral valve prolapse predisposition in Marfan patients.

International journal of cardiology - 24 Jan 2008

Fatini Cinzia, Attanasio Monica, Porciani Cristina, Sticchi Elena, Padeletti Luigi, Lapini Ilaria, Abbate Rosanna, Gensini Gian Franco, Pepe Guglielmina

Abstract excerpt

BACKGROUND: In Marfan syndrome, the mitral valve prolapse, ranging from nonclassic to classic form on the basis of the leaflet thickness, is a common condition characterized by a highly variable structural abnormality. We investigated the role of angiotensinogen (AGT) M235T, angiotensin converting enzyme (ACE) I/D and angiotensin II type 1 receptor (AT1R) A1166C polymorphisms in influencing the susceptibility to...

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Source

Identifiers

PMID: 17379330
DOI: 10.1016/j.ijcard.2006.12.015

Genes

ACE
AGT
MVP

Variants

Provenance

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Source receipt: pubmed, retrieved 7 Sept 2026.

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