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Article

A novel subunit of yeast RNA polymerase III interacts with the TFIIB-related domain of TFIIIB70.

Molecular and cellular biology - 1 Jan 2000

Ferri M L, Peyroche G, Siaut M, Lefebvre O, Carles C, Conesa C, Sentenac A

Abstract excerpt

There is limited information on how eukaryotic RNA polymerases (Pol) recognize their cognate preinitiation complex. We have characterized a polypeptide copurifying with yeast Pol III. This protein, C17, was found to be homologous to a mammalian protein described as a hormone receptor. Deletion of the corresponding gene, RPC17, was lethal and its regulated extinction caused a selective defect in transcription of...

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Identifiers

PMID: 10611227
DOI: 10.1128/MCB.20.2.488-495.2000
PMCID: PMC85110

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