Article
Genetic approaches in mice to understand Rel/NF-kappaB and IkappaB function: transgenics and knockouts.
Oncogene - 22 Nov 1999
Gerondakis S, Grossmann M, Nakamura Y, Pohl T, Grumont R
Abstract excerpt
Rel/NF-kappaB transcription factors have been implicated in regulating a wide variety of genes important in cellular processes that include cell division, cell survival, differentiation and immunity. Here genetic models in which various Rel/NF-kappaB and IkappaB proteins have either been over-expressed or deleted in mice will be reviewed. Although expressed fairly ubiquitously, homozygous disruption of individual...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
