Article
Validation of linkage by sampling based on environmental exposures.
Genetic epidemiology - 1 Jan 1999
Greenwood C M, Brewer C G, Morgan K
Abstract excerpt
After detecting linkage in one sample, most researchers will attempt to validate this finding in another sample. Three strategies for validating a primary linkage were compared, with a focus on methods that might be appropriate in the presence of gene x environment interaction. First, a validation sample was collected and analyzed using the same ascertainment procedure and methods as the primary sample. Second, a...
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