Article
Expression of costimulatory molecules in low-grade mucosa-associated lymphoid tissue-type lymphomas in vivo.
The American journal of pathology - 1 Dec 1999
Knörr C, Amrehn C, Seeberger H, Rosenwald A, Stilgenbauer S, Ott G, Müller Hermelink H K, Greiner A
Abstract excerpt
B-cell lymphomas of mucosa-associated lymphoid tissue (MALT) type develop against a background of chronic inflammation and have functional autoantigen receptors. Because they respond to environmental factors in vivo, the expression of costimulatory molecules, which play a key role in the differentiation of normal B-lymphocytes and in T-/B-cell interaction, may be critical in early MALT-type lymphoma pathogenesis...
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