Article
Expression of immune regulatory molecules in Epstein-Barr virus-associated nasopharyngeal carcinomas with prominent lymphoid stroma. Evidence for a functional interaction between epithelial tumor cells and infiltrating lymphoid cells.
The American journal of pathology - 1 Oct 1995
Agathanggelou A, Niedobitek G, Chen R, Nicholls J, Yin W, Young L S
Abstract excerpt
Undifferentiated nasopharyngeal carcinomas (UNPC) are characterized by an association with Epstein-Barr virus and an abundant lymphoid stroma. The role of this lymphoid stroma is uncertain but is mostly thought to represent an immune response against viral or tumor antigens. We have analyzed the...
Topics
- Carcinoma
- Epithelium
- Herpesvirus 4, Human
- Humans
- Immune System
- Lymphoid Tissue
- Nasopharyngeal Neoplasms
- Phenotype