Article
Inhibiting gap junctional intercellular communication alters expression of differentiation markers in osteoblastic cells.
Bone - 1 Dec 1999
Li Z, Zhou Z, Yellowley C E, Donahue H J
Abstract excerpt
Gap junctional intercellular communication (GJIC) may contribute to cellular differentiation. To examine this possibility in bone cells we examined markers of cellular differentiation, including alkaline phosphatase, osteocalcin, and osteopontin, in ROS17/2.8 cells (ROS), a rat osteoblastic cell line expressing phenotypic characteristics of fully differentiated osteoblasts. We utilized ROS rendered communication...
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