Article
Systemic immunological changes induced by administration of grass pollen allergens via the oral mucosa during sublingual immunotherapy.
International archives of allergy and immunology - 1 Nov 1999
Fanta C, Bohle B, Hirt W, Siemann U, Horak F, Kraft D, Ebner H, Ebner C
Abstract excerpt
Twenty-four patients suffering from grass pollen allergy underwent sublingual immunotherapy (SLIT) with standardized grass pollen extract for 1 year. In order to investigate immunological changes induced by the administration of allergens via the oral mucosa, the SLIT-spit method was applied. The cumulative dose of approximately 80 microg of major allergen (grass group 5 allergen), was relatively low. During the...
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