Article
Analysis of human T cell clones reactive with group V grass pollen allergens.
International archives of allergy and immunology - 1 Dec 1994
Müller W D, Karamfilov T, Fahlbusch B, Vogelsang H, Jäger L
Abstract excerpt
Twenty-seven T cell clones (TCC) reactive with group V allergens of Phleum pratense (Phlp V) were established from the peripheral blood of 3 patients allergic to grass pollen. Twenty-four TCC showed the helper cell phenotype CD3+, CD4+, CD8-; the remaining clones were CD3+CD4-CD8+. T cell recognition of Phlp V was exclusively HLA-DR restricted. Many of the Phlp V reactive TCC (19 of 27; 70%) were stimulated...
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