Article
High-resolution crystal structure and IgE recognition of the major grass pollen allergen Phl p 3.
Allergy - 1 Dec 2014
Devanaboyina S C, Cornelius C, Lupinek C, Fauland K, Dall'Antonia F, Nandy A, Hagen S, Flicker S, Valenta R, Keller W
Abstract excerpt
BACKGROUND: Group 2 and 3 grass pollen allergens are major allergens with high allergenic activity and exhibit structural similarity with the C-terminal portion of major group 1 allergens. In this study, we aimed to determine the crystal structure of timothy grass pollen allergen, Phl p 3, and to study its IgE recognition and cross-reactivity with group 2 and group 1 allergens. METHODS: The three-dimensional...
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