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Article

Relaxin promotes differentiation of human breast cancer cells MCF-7 transplanted into nude mice.

Virchows Archiv : an international journal of pathology - 1 Nov 1999

Bani D, Flagiello D, Poupon M F, Nistri S, Poirson-Bichat F, Bigazzi M, Bani Sacchi T

Abstract excerpt

Previous studies showed that the hormone relaxin acts on human breast cancer MCF-7 cells in vitro by modulating cell proliferation and promoting cell differentiation toward a duct epithelial phenotype. The present study was designed to investigate whether relaxin retains these properties when acting in vivo on MCF-7 cell tumors developed in athymic nude mice. Mice bearing MCF-7 cell tumors transplanted under the...

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Identifiers

PMID: 10592055
DOI: 10.1007/s004280050435

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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